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GK QUESTION#3659

Match the columns.

Read each row across both columns.

Column A (disorder)Column B (enzyme)
i. Gaucher diseasea. Phenylalanine hydroxylase
ii. Hunter syndromeb. Hexosaminidase
iii. Tay–Sachs diseasec. Iduronate-2-sulfatase
iv. Phenylketonuriad. Glucocerebrosidase
  1. Ai-a, ii-b, iii-c, iv-d
  2. Bi-b, ii-c, iii-a, iv-d
  3. Ci-d, ii-c, iii-b, iv-aCorrect answer
  4. Di-b, ii-a, iii-d, iv-c
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Answer

C. i-d, ii-c, iii-b, iv-a

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Explanation

The matching is Gaucher disease–glucocerebrosidase, Hunter syndrome–iduronate-2-sulfatase, Tay–Sachs disease–hexosaminidase A and phenylketonuria–phenylalanine hydroxylase. Thus i-d, ii-c, iii-b, iv-a is correct. These inherited disorders involve deficient activity of the corresponding enzymes.

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