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GK QUESTION#3636

In what condition does the body's immune system attack the actual intrinsic factor protein or the cells in your stomach lining that makes it?

  1. AWernicke - Korsakoff syndrome
  2. BHepatic cirrhosis
  3. CPernicious anaemiaCorrect answer
  4. DHartnup disorder
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Answer

C. Pernicious anaemia

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Explanation

Pernicious anaemia is an autoimmune cause of vitamin B 12 malabsorption. Immune injury to stomach parietal cells or antibodies against intrinsic factor impair the intrinsic-factor-dependent absorption pathway.

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