GK QUESTION#3593
Which essential micronutrient plays a clear role in the synthesis, storage and secretion of insulin in the hexameric form as well as in the conformational integrity of insulin?
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Answer
A. Zinc
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Explanation
Zinc ions coordinate insulin molecules in storage hexamers in pancreatic beta-cell secretory granules. The hexamers dissociate after secretion; the active circulating hormone is principally monomeric. The question’s hexamer clue identifies zinc among the choices.